Job Description
We are seeking a motivated scientist in areas of protein design and production. A successful candidate should play key roles in target validation and protein design and production, hit identification, hit validation by biophysical method.
Major Responsibilities
- design, express/purify, and characterize proteins of therapeutic interest.
- perform SPR or other biophysical assay to characterize protein-ligand, protein-protein interactions.
- protein crystallization and X-ray.
Minimum Requirements
- MS or BS (or relevant experience) in protein chemistry, biochemistry, enzymology or biophysics with 2-3 years of drug discovery experience. Experience in pharmaceutical or biotech company is preferred.
- Solid knowledge and experience in expression vector construction, multiple protein expression systems and various purification techniques.
- Expertise in biophysical techniques including SEC-MALS, SPR, ITC and TSA, etc.
- Experience working in new directions, building new platforms or bringing in new methods/technologies in protein science.