Sr./Principal Data Engineer


About TandemAI

TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution.

About the Role

The Sr./Principal Data Engineer will lead the design of world-class infrastructures for data management and computational processing workflows that seamlessly integrates data from computational calculations and wet-lab experiments to enable the rational design of therapeutics.

You will:

  • Work closely with multidisciplinary teams of computational and medicinal chemists, data and software engineers, biophysicists, and biologists to optimize our computational platform, guide synthesis decisions, and design experiments
  • Define the high-level architecture of the data platform, and create execution plans to implement and deliver the platform
  • Identify data access requirements from various stakeholders, and design effective interfaces to meet those needs
  • Develop and deploy software tools that allow our scientists to easily access, and take full advantage of, experimental data and computational methodologies
  • Ensure the availability, integrity, security and reliability of our data platform


  • PhD/Master degree in Computer Science or a related technical field with 5+ years relevant industrial experience
  • Experience in design and implementation of analytics data platforms that support heterogeneous data types and diverse workloads/dataflows
  • Experience with data warehouse and/or data lake solutions
  • Development experience with big-data technologies, data pipelines, and orchestration tools
  • Strong programming skills in a modern language such as Python and Java
  • Familarity with data science frameworks such as MLflow and Metaflow
  • Strong analytical and problem solving skills
  • Excellent written and oral communication skills, including an ability to explain complex ideas to non-specialists

Desired Qualifications

  • Experience with data systems that support machine learning workflows and data lifecycle
  • Experience with computational chemistry, chemoinformatics, molecular dynamics simulations, and drug discovery

At TandemAI, we are committed to building a world-class team whose culture is founded on collaboration, intellectual curiosity, trust, and respect. We firmly believe that our exceptional staff will be the key to our success and are committed to high standards and rigorous science. Because of this, we are prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare, a 401k, pre-tax commuter benefits, and a flexible work schedule.

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