Reduce your drug discovery timelines and increase cost efficiencies by leveraging the power of digital assays and workflows.
Reducing the number of compounds you need to synthesize and assay in the wet lab enables higher throughput and lower costs for your entire workflow.
By integrating digital assays into your workflow, you can expand your design space by 5 times and reduce your hit-to-lead and lead optimization timelines by at least 50%, allowing you to discover more - faster.
Compute protein-small molecule binding affinities to near experimental accuracy using our free energy perturbation (FEP) potency assay, TandemFEP, which utilizes small molecule force field parameters rigorously derived from quantum mechanics calculations.
Predict absorption, distribution, metabolism, excretion, and toxicity (ADMET) endpoints for all small molecule candidates using TandemADMET, built on machine-learning models with industry-leading accuracy.
Utilize the generative AI and library-based small molecule ideation in TandemGen to rapidly enumerate high-quality and novel small molecule candidates. Predict with confidence using our meticulously curated feature, TandemFilters, designed by our medicinal chemists, to ensure our generated molecules are chemically reasonable.
Exhaustively enumerate, evaluate, and synthesize the top analogs in your series in a single workflow that combines the power of TandemGen, TandemFEP, and combinatorial chemistry.
Rigorously identify new cores for any chemical series in a single workflow, utilizing generative design from TandemGen and our proprietary CoreHop-FEP.
Utilize our multi-tiered approach for accurate ternary complex structure prediction from individual protein and ligase structures with our ternary complex modeling platform (beta).
Screen billions of molecules against your protein binding pocket using a number of commercial and bespoke designed libraries with our proprietary AI-powered vHTS workflow.
Combine computational and experimental data with our powerful analytics interface, TandemAnalytics, to derive dynamic structure-activity relationships for small molecules at the atomic level.
By harnessing the power of digital analysis packages, you can generate more data than is possible from traditional wet lab assays alone.
Our digital potency assays provide you with far more than just a single potency value per compound, expanding on this with trajectory movies from our computational microscope to give atomic insight into how the small molecules interact with proteins.
We understand that it is critical for the technology you invest in to create a reliable foundation of data on which to base your research. That’s why we are dedicated to ensuring the predictions from all our digital assays and workflows achieve or surpass industry benchmarks for accuracy and reliability.
Available by FTE, where you pay for wet lab services and gain complimentary access to our proprietary computational tools or software license (SaaS), with optional GPU services, virtual private cloud (VPC) deployment, and expert application support.
