Integrating with our cutting-edge computational tools, our synthetic and medicinal chemistry services fulfill the “design-make-test” cycle with real compound preparation by our richly and diversely experienced team, with dedicating attitude to client service, and first-line wet chemistry lab hardware and instrumentation.
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Since 2022, our synthetic chemistry team has experienced rapid expansion, now boasting over 200 chemists. Their collective expertise spans a diverse array of chemotypes, and their extensive experience in project and team management has cemented a successful track record in project delivery.
This optional module encompasses a comprehensive range of services, including competitive landscape analysis, patent analysis, hit identification, and hit-to-lead optimization support.
Our team's expertise extends beyond small molecules, encompassing a wealth of experience with various modalities such as PROTACs, molecular glues, conjugated drugs (including pro-drugs and others, up to OEB-4 potency), and developing peptide capabilities is within our next vision.
We pride ourselves on our special capabilities, which include metal catalysis high-throughput screening, photochemistry, microwave reactors, and the synthesis of stable isotope-labeled compounds.
Medicinal chemistry support is available as a supplementary module for your discovery project, offering the flexibility to tailor our services to your specific needs. Our medicinal chemistry specialists bring a wealth of experience in structure-based drug design (SBDD) and traditional drug design methodologies, catering to a variety of targets across numerous therapeutic areas. Their proven success in delivering preclinical candidates (PCCs) is a testament to the exceptional quality of our medicinal chemistry services.
This optional module encompasses a comprehensive range of services, including competitive landscape analysis, patent analysis, hit identification, and hit-to-lead optimization support.
Equipped with full spectrum first-line equipment and software, our analytical service can support discovery programs in high efficiency and low turnaround time.
While most services are bundled with synthetic chemistry, our analytical service team can work on standalone requests such as chiral resolution, impurity studies, structural elucidation, among others.
Process research, also known as route scouting, is an upstream endeavor of process development and manufacturing, and is an entry point for leveraging such efforts for future preparation. It can significantly reduce the cost, improve the safety profile, and improve the scalability of the route.
Special request can be made at late-PCC declaration stage for either certain intermediate or the whole molecule.
This would allow either a possibility to expand the chemistry space for new ideas/entrance in the discovery stage, or a pre-study for IND enabling studies in the next phase.
Note: Certain services in this area will be performed in collaboration with other CDMOs in the field, and project management service can be additionally provided.
We are compliant with IP protection and data management. Data are electronically recorded, access controlled, and stored in in-house servers. Intensive infrastructure on EHS has been invested and well maintained.
Available by FTE, where you pay for wet lab services and gain complimentary access to our proprietary computational tools or software license (SaaS), with optional GPU services, virtual private cloud (VPC) deployment, and expert application support.
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